reducing body fat associated with a maintained fat-free
mass represents an important factor to prevent the weight
regain [33]. In the current study, eating carbohydrates
mostly at lunch associated with eating protein mostly at
dinner contributed to the preservation of the fat-free mass
since its decrement was not significant only in the DCNP.
Sofer et al. [14] investigated the effect of a low-calorie diet
(1,300–1,500 kcal) for 6 months, with carbohydrates eaten
mostly at dinner, and found higher reduction in body
weight, waist circumference, and fat mass compared with
control. In turn, Golay et al. [13] evaluated the effect of a
low-caloric (1,000 kcal/day) and high-protein diet on the weight loss of obese subjects, during 6 weeks, with a
high-protein lunch and a high-carbohydrate dinner, but significant
difference was no found between control and
experimental diet group for weight loss. Overall, the highprotein
dinner may contribute for a protein oxidation in order
to maintain the glucose homeostasis during the fasting period
at night since the dinner was a low-carbohydrate meal. Thus,
the body fat-free mass would be spared in DCNP by using the
eaten protein as an energy substrate, although the mechanisms
must still be elucidated by further researches
reducing body fat associated with a maintained fat-free
mass represents an important factor to prevent the weight
regain [33]. In the current study, eating carbohydrates
mostly at lunch associated with eating protein mostly at
dinner contributed to the preservation of the fat-free mass
since its decrement was not significant only in the DCNP.
Sofer et al. [14] investigated the effect of a low-calorie diet
(1,300–1,500 kcal) for 6 months, with carbohydrates eaten
mostly at dinner, and found higher reduction in body
weight, waist circumference, and fat mass compared with
control. In turn, Golay et al. [13] evaluated the effect of a
low-caloric (1,000 kcal/day) and high-protein diet on the weight loss of obese subjects, during 6 weeks, with a
high-protein lunch and a high-carbohydrate dinner, but significant
difference was no found between control and
experimental diet group for weight loss. Overall, the highprotein
dinner may contribute for a protein oxidation in order
to maintain the glucose homeostasis during the fasting period
at night since the dinner was a low-carbohydrate meal. Thus,
the body fat-free mass would be spared in DCNP by using the
eaten protein as an energy substrate, although the mechanisms
must still be elucidated by further researches
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