We used the binary indicators of full adherence during
the 2 to 4 months immediately following statin initiation and baseline patient clinical and
demographic characteristics to predict
each patient’s observed 12-month adherence
trajectory. To predict membership
in a given trajectory, we estimated a multivariable
logistic regression model with
the trajectory group of interest compared
with all others as the outcome. All models
were run separately based on the length
of the patient’s index statin fill (ie, ≤30
and >30 days’ supply); prior research has
demonstrated important differences in the
discriminative ability of predictive models
based on this stratification factor.