However, in recent years the field of sweet taste has experienced a sudden twist due to the presence of taste receptors (TR) not only in clusters in the oral cavity (taste buds) but also in non-taste tissues particularly in the mucosa of the GIT. It is believed that the TR expression in the GIT mucosa is related to post-ingestive events such as the recognition of nutrients in the lumen (i.e. glucose) and the facilitation of digestion and absorption (Dyer et al. 2005, Mace et al. 2009).