We used group-based trajectory models to classify
patients into 6 adherence trajectories based on patterns of statin
filling over the year following therapy initiation. Baseline clinical
characteristics and indicators of statin filling during the first 2 to 4
months following initiation were used to predict adherence trajectory
in logistic regression models, separately within strata of the
days’ supply of the initial statin dispensing. Cross-validation was
used to measure predictive accuracy of models in data not used
for model estimation.