2.3. Anti-M. tuberculosis activity assay
The in vitro anti-M. tuberculosis activity of SFE-CO2 extracts and
the benzoic acid derivative (1) from P. diospyrifolium leaves was
evaluated using REMA. All tested SFE-CO2 extracts showed
moderate activity against M. tuberculosis H37Rv ATCC 27294 with
MIC values of 125 mg/mL (Table 3). The operating conditions used
to obtain the SFE-CO2 extracts did not affect the anti-M.
tuberculosis activities, since their MICs remained the same for all