This paper aims to effective combination between college physics and multimedia to optimize the teaching procedure of physics as a serious basic course in college. Through combining multimedia technology with the teachers’ subjective initiative, perfecting multimedia course system based on the network, multimedia simulation laboratory organic coupling with real experimenting, we discusses how the actual teaching use of multimedia technology, explore the application of the rules and characteristics of multimedia technology. we are able to develop the advantages of multimedia and explore its potential so that we make it better service in physics teaching and enhance teaching effect.