Consistent with this assumption, an adaptation of the oral lipid
sensing system in function of the lipid content of diet was sus-
pected. Indeed, it was previously shown a lipid-mediated down-
regulation of CD36 in intestinal cells
[21]
. As expected, CD36 pro-
tein level in circumvallate papillae (CVP) displays a diurnal rhythm
with a down-regulation during the dark period corresponding to
the food intake