Experimental design: The diabetic rats were acclimatized for 1 week and then divided into six groups as follows:
Group 1: The rats received oral saline 10 mL kg-1 BW (control group)
Group 2: The rats received andrographolide dose 1.5 mg kg-1 b.wt orally, twice daily
Group 3: The rats received andrographolide dose 4.5 mg kg-1 b.wt orally, twice daily
Group 4: The rats received andrographolide-enriched extract of A. paniculata (Burm. f.) Nees (AEEAP) dose 434.6 mg kg-1 b.wt orally, twice daily
Group 5: The rats received AEEAP dose 1303.8 mg kg-1 b.wt orally, twice daily
Group 6: The rats received glibenclamide dose 45 mg kg-1 b.wt orally, twice daily