Researchers are also investigating inflammatory mediators, such as Tumor Necrosis Factor α (TNF-α), Interleukin-1β (IL-1β) Interleukin-6 (IL-6), Interleukin-8 (IL-8) and Interleukin-10 (IL-10) [9–11]. Atypical pathogens, especially Ureaplasma spp., are believed to play a particular role in the inflammatory reaction leading to BPD .