Conclusions
This study demonstrated excellent
test-retest reliability for the TUG, the
6MWT, and gait speed in individuals
w^ith AD. Significant differences
were found in performance of these
outcome measures between the mild
to moderate AD group and the moderately
severe to severe AD group,
with the participants who were less
cognitiveiy impaired outperforming
those who were more cognitiveiy
impaired. Despite very high ICCs for
test-retest reliability, there was notable
individual variability in the performance
of these measures. Presentation
of SEM and MDCgo, for each of
the measurement tools, provides clinicians
with meaningful thresholds
for identifying changes beyond those
expected from measurement error
and individual variability (ie, "true"
change) in individuals with AD. We
ConclusionsThis study demonstrated excellenttest-retest reliability for the TUG, the6MWT, and gait speed in individualsw^ith AD. Significant differenceswere found in performance of theseoutcome measures between the mildto moderate AD group and the moderatelysevere to severe AD group,with the participants who were lesscognitiveiy impaired outperformingthose who were more cognitiveiyimpaired. Despite very high ICCs fortest-retest reliability, there was notableindividual variability in the performanceof these measures. Presentationof SEM and MDCgo, for each ofthe measurement tools, provides clinicianswith meaningful thresholdsfor identifying changes beyond thoseexpected from measurement errorand individual variability (ie, "true"change) in individuals with AD. We
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