This paper develops and illustrates an effective method to explore an optimal policy combination (OPC)
for total water pollution control in a river basin through constructing a dynamic optimization simulation
model consisting of socioeconomic model, water pollutant model and energy model based on input
eoutput approach. The impacts induced by the introduction of water pollution control policies on
economic development and industrial restructuring with water pollutant discharge constraints have
been comprehensively evaluated within the horizon of 2011e2020. Based on the objectives of local
economic development and water pollution control, the model obtains a global optimal solution with
consideration of the full effects. The OPC and industrial restructuring collectively contribute to meeting
the water pollutant discharge constraints. The changing trends in pollutant discharge structure and
sectoral production are traced after deriving the OPC. The OPC influenced by the diversity and efficiency
of policies and constraint settings is specified through clarifying the implementation of each policy and
technology that contribute to the reduction in water pollutants promoted by the subsidies. This study
helps to realize regional sustainable development by manifesting the best trade-off between economic
development and water environmental conservation as well as effectiveness of policies adopted.