Materials and methods
We performed a retrospective chart review of the first
80 patients with partial seizures put on topiramate after
approval for clinical use from 16 January 1997 to
15 April 1997 at the University of Alabama at Birmingham
Epilepsy Center. Patients who developed symptoms
of psychosis such as hallucinations and delusions
were included. Patients with cognitive impairment such
as slowed thinking, psychomotor slowing, language
impairment, confusion, symptoms of depression, crying
spells, and impairment of sleep were not included.
Five patients with a history of partial seizures, aged
27 years to 62 years, three men and two women, met
criteria for a diagnosis of psychosis.
Materials and methods
We performed a retrospective chart review of the first
80 patients with partial seizures put on topiramate after
approval for clinical use from 16 January 1997 to
15 April 1997 at the University of Alabama at Birmingham
Epilepsy Center. Patients who developed symptoms
of psychosis such as hallucinations and delusions
were included. Patients with cognitive impairment such
as slowed thinking, psychomotor slowing, language
impairment, confusion, symptoms of depression, crying
spells, and impairment of sleep were not included.
Five patients with a history of partial seizures, aged
27 years to 62 years, three men and two women, met
criteria for a diagnosis of psychosis.
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