Figure 3. The effects of FLC or the combined compounds 3 and 8 on the activity of efflux pumps. (A) The measurement of Rh123 efflux, induced through glucose in the FLC-resistant strain 24D, was assessed using flow cytometry detection. (B) The intracellular accumulation of Rh123 in C. albicans cells in response to treatment with compound 3 (16μg/ml) or 8 (16μg/ml) was revealed through CLSM observation.