Treatments : A hospital stay is usually necessary to lessen the inflammation of your gallbladder. You may be required to not eat or drink (fast) for a certain amount of time. You may be given medicine to treat pain or an antibiotic medicine to treat an infection. Surgery may be needed to remove your gallbladder (cholecystectomy) once the inflammation has gone down. Surgery may be needed right away if you develop complications, such as a tear (perforation) of the gallbladder or death of gallbladder tissue (gangrene)