Sediment and water samples were collected from hyper saline soda lakes in Wadi El-Natrun Valley that are located in northern Egypt (Fig. 1). The Valley contains alkaline inland saline lakes in an elongated depression approximately 90 km northwest of Cairo (capital of Egypt). The average length of the valley is nearly 60 km, and its average width is approximately 10 km. Wadi El-Natrun Valley extends in a northwest by southeast direction between latitude 30°15′ North and longitude 30°30′ East. The bottom of the Valley is 23 m and 38 m below sea level, and water level of Rosetta branch of the Nile, respectively [18]. Sediment and water samples were collected from various hyper saline soda lakes in sterile containers, kept at 4°C, and transferred within few d to the laboratory at King Saud University (Riyadh,Saudi Arabia).