Results: General fatigue correlated with FEV1? percent predicted (r = .0.32, p < 0.05), exercise
tolerance (r = .0.55, p < 0.05), depression (r = 0.44, p < 0.01), and overall quality of life
(r = 0.75, p < 0.01). Among the dimensions of fatigue, depression correlated with general and
mental fatigue only. Physical dimensions of fatigue correlated with an increase in the severity of
pulmonary impairment and reduction in exercise tolerance. The cognitive components of fatigue,
such as reduction in motivation and mental fatigue, were not found to be highly correlated with
physical dimensions of quality of life. All five subscales of fatigue showed relationship to the
functional impact dimension and total impairment score in quality of life.
Conclusions: These data show a relationship between dimensions of fatigue and pulmonary
function, exercise tolerance, and quality of life in COPD. Based on these results, fatigue is an
important symptom requiring evaluation and management in patients with COPD. These data
clarified also the relationship between depression and fatigue in this patient population.
(CHEST 1998; 114:958-964)
Key words: COPD; fatigue; quality of life
Abbreviations: CES-D = Centers of Epidemiological Studies Depression Scale; MFI-20 = Multidimensional Fatigue
Inventory; SGRQ = St. George Respiratory Questionnaire; 6MD = 6-min walking distance test
Results: General fatigue correlated with FEV1? percent predicted (r = .0.32, p < 0.05), exercise
tolerance (r = .0.55, p < 0.05), depression (r = 0.44, p < 0.01), and overall quality of life
(r = 0.75, p < 0.01). Among the dimensions of fatigue, depression correlated with general and
mental fatigue only. Physical dimensions of fatigue correlated with an increase in the severity of
pulmonary impairment and reduction in exercise tolerance. The cognitive components of fatigue,
such as reduction in motivation and mental fatigue, were not found to be highly correlated with
physical dimensions of quality of life. All five subscales of fatigue showed relationship to the
functional impact dimension and total impairment score in quality of life.
Conclusions: These data show a relationship between dimensions of fatigue and pulmonary
function, exercise tolerance, and quality of life in COPD. Based on these results, fatigue is an
important symptom requiring evaluation and management in patients with COPD. These data
clarified also the relationship between depression and fatigue in this patient population.
(CHEST 1998; 114:958-964)
Key words: COPD; fatigue; quality of life
Abbreviations: CES-D = Centers of Epidemiological Studies Depression Scale; MFI-20 = Multidimensional Fatigue
Inventory; SGRQ = St. George Respiratory Questionnaire; 6MD = 6-min walking distance test
การแปล กรุณารอสักครู่..
