Aquilaria species is an aromatic plant that is commonly known as “Gaharu wood” in South East Asia
[1]. It is found mostly in Malaysia, Indonesia, India, Iran, Singapore, Bangladesh, Myanmar, Philippine,
and Thailand [2]. A. malaccensis produces valuable resin marinate in the heartwood. This resin originates
as a consequence of natural immune response towards fungal attack. Endophyte is a fungus that lives
inside healthy plant tissues, some of these endophytes have been found to have anticancer and antidiabetic
properties [2,3]. It is well known that the essential oil of A. malaccensis is safe, simple to
produce and commonly used in traditional medicine to relive pain, fever, rheumatism and asthma. A
number of compounds have been extracted from A. malaccensis such as alkaloids, tannins, phenols,
terpenoids, Quinones and