Our results showed that the EPA-rich CO was as efficient as FO at enriching liver EPA in a dose-dependent manner. Many rodent studies reported increases in hepatic EPA and DHA after FO supplementation, with the enrichment being variable and
dependent on the EPA+DHA dose, the EPA to DHA ratio, and the overall composition of the diets (48, 58, 59). Increases in EPA, observed after COH and FOH feeding, were comparable to those reported for the phospholipid fraction of liver from mice fed an FO providing comparable EPA intakes (59).
Our results showed that the EPA-rich CO was as efficient as FO at enriching liver EPA in a dose-dependent manner. Many rodent studies reported increases in hepatic EPA and DHA after FO supplementation, with the enrichment being variable anddependent on the EPA+DHA dose, the EPA to DHA ratio, and the overall composition of the diets (48, 58, 59). Increases in EPA, observed after COH and FOH feeding, were comparable to those reported for the phospholipid fraction of liver from mice fed an FO providing comparable EPA intakes (59).
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