Whereas quasi-experimental and experimental approaches provide information about which instmctional methods are most effective in a general sense, qualitative research helps establish which contextual factors may influence the success of an approach. Mixed methods can lead to insights about possible challenges to implementation as well as the circumstances underwhich a practice is most likely to be successful, adding depth and breadth not available through quantitative designs alone. We propose that it is not enough to ask, "What works?" Researchers must also ask, "What works with whom, by whom, in what contexts, under what circumstances, and for what purposes?" (Klingner & Edwards, 2006).