DLD-1 cells via affecting the expression of cyclins, cdc2 and p27.
This discrepancy might be due to the difference in cell type analysed.
The G1 phase of cell cycle is controlled by cyclin dependent
kinases, cyclin kinase inhibitors and cyclins (Mantena et al., 2006).
To investigate the precise molecular mechanism of G1 phase arrest
induced by c-mangostin and 8-deoxygartanin in SK-MEL-28 cells,
further experiments are currently being carried out into changes
related to these controllers.