This paper evaluates the implementation of the 2010–2015 ASEAN Strategic Action Plan for Small and Medium Enterprises (SME) Development and the 2004–2009 ASEAN Policy Blueprint for SME Development. The initial interviews and survey results yielded low average effectiveness scores for the ASEAN Strategic Action Plan for SME Development. The scores ranged from without- to no- or little concrete impacts on the implementation of various programs covering access to financing, facilitation, technology development, promotion, human resource development, and other regional SME initiatives.