Subjects and Methods
The DREW trial is described in detail elsewhere (6). In brief, 464 eligible postmenopausal
women (45–75 years old) were randomized to a non-exercise control group or to one of three
exercise groups that provided 50%, 100% and 150% of the NIH Consensus Development Panel
recommendations for physical activity (4, 8 or 12 kcal/kg/wk respectively) (7). Eligible
participants had to be sedentary (≤20 minutes of exercise