Streptomyces soil rot or pox is a widespread disease of sweet potato in North Carolina that results in a reduction in plant growth and severe yield losses. It is caused by thesoilborne filamentous bacterium, Steptomyces ipomoea, and is able to persist in soil for many years in the absence of sweet potatoes. Fibrous roots and storage roots are infected in the field and symptom development varies based on the timing of root infection (Figure 1). Disease is favored by dry soils with pH above 5.2.