Conclusion: Compared with usual care, PST with or without PSM
is associated with significantly fewer deaths and thromboembolic
events, without increased risk for a serious bleeding event, for a
highly selected group of motivated adult patients requiring longterm
anticoagulation with vitamin K antagonists. Whether this care
model is cost-effective and can be implemented successfully in
typical U.S. health care settings requires further study.
Primary Funding Source: U.S. Department of Veterans Affairs