The critical care nurse can use the synergy model for patient care as a theoretical framework to evaluate evidence-based practice related to ventilator care. In the 1990s, the American Association of Critical Care Nurses presented a new paradigm for clinical practice that transcended the current perspective of the task-oriented practice. This new synergy model for patient care is a practice model that focuses on a healthcare system guided by the patients’ needs in which nurses make optimal contribution to patients’ outcomes.