Therefore it would appear that the toxicity was not transmitted
into the milk since not even a fraction (I/49~ or I/3O8) of the activity
of the pigment glands consumed by the cows could be detected in the
milk by feeding it to rats.
It would also appear that no appreciable amounts
of gossypol were transmitted into the milk since none of the appetite depres.
sing effects associated with gossypol (Zucker et al., I947 and Eagle I949)
were seen in the rats. Since approximately ~o% of the pigment gland is
gossypol, relatively large amounts of gossypol were consumed by the cows.
Even though the milk appeared to be free of any toxicity as tested with the
rat, this does not preclude the possibility that still other factors may exist
in the milk which might provoke an allergic reaction particularly in the human
consuming the milk..