The objectives of this study were to establish the level of prescription drug safety knowledge in older adults and assess pharmacy readiness to promote prescription drug safety in pharmacies. In the first part of the survey, patients indicated high levels of belief about the issues surrounding interactions between alcohol and prescription medication, with women tending to show a greater understanding. However, across genders, participants were not very aware that alcohol consumption at any level can be harmful, and that it is important to refrain from drinking more than one drink a day. These latter two findings suggest that while participants were mostly aware that alcohol and prescription medications can interact with undesired consequences, they were less aware of how even low levels of alcohol consumption can be harmful, and that they should monitor their personal levels of alcohol consumption.