Organophosphorus pesticides are used widely for agriculture,
vector control, and domestic purposes.
Despite the apparent benefits of these uses acute
organophosphorus pesticide poisoning is an increasing
worldwide problem, particularly in rural areas.
Organophosphorus pesticides are the most important
cause of severe toxicity and death from acute poisoning
worldwide, with more than 200 000 deaths each
year in developing countries.1 Although the incidence
of severe acute organophosphorus pesticide poisoning
is much less in developed countries, many patients
with low dose acute unintentional or occupational
exposures present to health facilities.23 We provide
an evidence based review of the management of
acute organophosphorus pesticide poisoning.