Anesthetics are used in fish husbandry and management to minimize stress during routine procedures, such as handling the fish. The tested doses of clove oil and quinaldine were 20, 40, 80 and 120 ppm, while the tested concentrations of AQUI-S were 20, 40 and 60 ppm. All the tested concentrations of the three drugs were effective on the tested fish from the two species to reach the total sleep and recover with no mortality. All the fish were observed for 96 h with no change in behavior or feeding.