The DSS is developed to compute the MSY from the annual yield-effort data of the fishery. We use two sigmoid growth equations, Logistic and Gompertz equations, as the underlying population models, which then are approximated by their discrete forms for computing several growth parameters. Most known methods of growth parameter estimation use a Multiple Linear Regression with Ordinary Least Square method (MLR-OLS). Here we propose the application of Artificial Neural Network with Linear Perceptron method (ANN-LP). A case study in this paper shows that the effectiveness of the proposed ANN-LP is as good as the MLR-OLS in estimating both the growth parameters and the MSY of the fishery in the case study.