The results of the surveys and interviews showed that the reasons of most fears and poor cooperation of the children with the insulin injections were fear of pain, damage to the body, and the fatigue associated with its daily repetition. One eight-year-old girl stated, “I don’t want to inject insulin, because I’m afraid of its needle.” A four-year-old girl stated, “I did not let my mom inject insulin into my stomach, because I’m afraid of making a hole in my stomach.” One six-year-old boy who was recently diagnosed with diabetes asked, “Why do I inject insulin?” According to the characteristics of computer games, most children preferred competitive and adventure games, cartoon characters, and human-like animation. The story of the game also was important to them, and they wanted the game to be designed in a medical setting, such as a hospital with a medical, attractive, funny, and happy scenario, and they wanted their medical questions on insulin and diabetes to be answered in this game.