Autosomal dominant polycystic kidney disease is a multisystem disorder, and some patients develop associated intracranial aneurysms, which can cause stroke and intracranial hemorrhage. Much of the morbidity of autosomal dominant polycystic kidney disease is due to chronic hypertension. Autosomal dominant polycystic kidney disease can manifest in utero with the Potter phenotype, with death from pulmonary hypoplasia