INTRODUCTION
Marine environments are largely untapped source for the isolation of new microorganisms with potentiality to produce active secondary metabolites. Among such microorganisms, Actinomycetes are of special interest, since they are known to produce chemically diverse compounds with a wide range of biological activities (Bredholt et al., 2008). The demand for new antibiotics continues to grow due to the rapid emerging of multiple antibiotic resistant pathogens causing life threatening infection. Although, considerable progress is being made within the fields of chemical synthesis and engineered biosynthesis of antibacterial compounds, nature still remains the richest and the most versatile source for new