functional, patient-tailored exercises, targeting specific daily activities which were indicated to be relevant and problematic by the patients themselves, and aerobic training (e.g., cross-trainer, treadmill) were added to the program. Training intensity and knee load further gradually increased each week to maximum level as possible, targeting maximal muscle power. In addition, knee stabilization training further increased in difficulty. Exercises consisted of three sets of 10 repetitions. Finally, participants were encouraged to remain physically active after completion of the exercise program. See supplementary file for more detailed information.