with a layer of microparticles
(Fig. 1, lower), the dimensions of the air channels
will be much smaller in the former; thus, the
hydrodynamic evaporation of water will decrease.
On the contrary, larger pores will facilitate the
water loss from the surface of the skin and
enhance the moisture loss. In certain conditions,
e.g. when the horny layer of the skin has become
macerated, an increased rate of moisture loss may
be desired. By manipulating the particle size of lipid
nanoparticles, different effects can be obtained