Modern medical and surgical practices have increasingly utilized
implantable medical devices of various kinds. Such devices
may be utilized only short-time or intermittently, for months,
years or permanently. They improve the therapeutic outcome,
save human lives and greatly enhance the quality of life of these
patients3. However, plastic devices are easily colonized with
bacteria and fungi, able to be colonized by microorganisms at a
rate of up to 0.5 cm per hour. A thick biofilm is formed within 24
hours on the entire surface of these plastic devices once inoculated
even with a small initial number of bacteria.