Comparison of the women who proceeded to abnormal
glucose tolerance (AGT, i.e. pre-diabetes or diabetes) after
GDM in the index pregnancy to those who had GDM
but maintained NGT during the follow-up, showed that
the individuals with AGT were significantly older dur-
ing the index pregnancy (P = 0.016) and at the time of
the follow-up study (P < 0.001), but had also a longer
follow-up time (P = 0.008) (Table 4). The women with
AGT at follow-up had higher BMI in the first trimester
of the index pregnancy and also at the follow-up study
visit (P = 0.001 and P < 0.001, respectively). The mean
difference in waist circumference was 7.0 cm between
the progressors and non-progressors (94.0 cm and
87.0 cm, respectively, P < 0.001). Peripheral insulin
sensitivity (Matsuda ISI) was significantly decreased in
patients with AGT (P < 0.001), and insulin secretion
(DI30) was markedly lower in the AGT group as com-
pared to NGT group (P < 0.001).
Comparison of the women who proceeded to abnormal
glucose tolerance (AGT, i.e. pre-diabetes or diabetes) after
GDM in the index pregnancy to those who had GDM
but maintained NGT during the follow-up, showed that
the individuals with AGT were significantly older dur-
ing the index pregnancy (P = 0.016) and at the time of
the follow-up study (P < 0.001), but had also a longer
follow-up time (P = 0.008) (Table 4). The women with
AGT at follow-up had higher BMI in the first trimester
of the index pregnancy and also at the follow-up study
visit (P = 0.001 and P < 0.001, respectively). The mean
difference in waist circumference was 7.0 cm between
the progressors and non-progressors (94.0 cm and
87.0 cm, respectively, P < 0.001). Peripheral insulin
sensitivity (Matsuda ISI) was significantly decreased in
patients with AGT (P < 0.001), and insulin secretion
(DI30) was markedly lower in the AGT group as com-
pared to NGT group (P < 0.001).
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