In conclusion, a six-week PMT and IMT methods improve respiratory functions, exercise capacity, and biochemistry markers in CAD patients with MetS. We can recommend different respiratory muscle training methods before traditional exercise training in complicated CAD with lower exercise capacity to tolerate exercise well. However, NMES for respiratory muscle training is a safe method and can be recommended also in patients with lower cardiovascular functions and exercise intol- erance who cannot participate in traditional cardiopulmonary rehabil- itation programs. More importantly, positive results can be achieved with PMT.