Objectives: To study the effect of unsupported upper limb and lower limb exercise training and their combined influence
on the exercise performance and health-related quality of life in COPD patients. Materials and Methods: Thirty patients
were randomly assigned to one of the three groups, through block randomization. Of the three groups, group A received
upper limb training, group B received lower limb training, and group C received both upper and lower limb training.
Patients in group A, B, and C underwent exercise training five times a week for four weeks. The outcome measures
used in the study were unsupported upper limb endurance test (UULEX), Six-Minute Walk Test (6-MWT), and a Chronic
Respiratory Questionnaire. Statistical analysis was performed with analysis of variance, Wilcoxon scale, and a Kruskal
Wallis one way ANOVA test, and a P value of .05 was used in the study. Conclusion: The combined upper limb and
lower limb training group showed a significant improvement in the exercise performance and health-related quality of life.