Abstract: Using Satellite Remote Sensing and Geographic Information System, this paper analyzes the land use and land cover change dynamics in the Bosomtwe District of Ghana, for 1986, 2010 thematic mapper and enhanced thematic Mapper+ (TM/ETM+) images, and 2014 Landsat 8 Operational Land Imager and Thermal Infrared Sensor (OLI/TIS) image. The three images were geo-referenced and processed for classification, using the maximum likelihood classifier algorithm