Moreover, apart from the synthesized TiO2 material, the commercial nano TiO2 powder (Aladdin, T104936) as well as previously reported TiO2@SiO2 particles31 were also used to investigate the universality of this adsorbing mechanism.
Because of the small dimension (not suitable for packing in the column), these TiO2 materials were directly used as the dispersed-SPE (DSPE) media to extract ribonucleosides.
After extraction of the mixture of adenosine and 2′-deoxyadenosine, the signal intensities of adenosine obviously decreased for all the groups (Figure S2 in the Supporting Information).
This result clearly indicated a general existence of such affinity interaction of TiO2 toward ribonucleosides.
Additionally, we also found that, with the increase of the calcinating temperature (up to 700 °C), all the materials would gradually lose the adsorbing capability for ribonucleosides, which was possibly caused by the decrease of the surface area and the removal of hydroxyls on TiO2.
Moreover, apart from the synthesized TiO2 material, the commercial nano TiO2 powder (Aladdin, T104936) as well as previously reported TiO2@SiO2 particles31 were also used to investigate the universality of this adsorbing mechanism.
Because of the small dimension (not suitable for packing in the column), these TiO2 materials were directly used as the dispersed-SPE (DSPE) media to extract ribonucleosides.
After extraction of the mixture of adenosine and 2′-deoxyadenosine, the signal intensities of adenosine obviously decreased for all the groups (Figure S2 in the Supporting Information).
This result clearly indicated a general existence of such affinity interaction of TiO2 toward ribonucleosides.
Additionally, we also found that, with the increase of the calcinating temperature (up to 700 °C), all the materials would gradually lose the adsorbing capability for ribonucleosides, which was possibly caused by the decrease of the surface area and the removal of hydroxyls on TiO2.
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