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John W. Martyny et al. (2004) Results: Both sodium hypochlorite disinfectants killed A fumigatus in solution and on mold-contaminated building materials. Light microscopy and scanning electron microscopy demonstrated changes to the conidial surface. Both dilute bleach and Tilex inhibited A fumigatus recognition by ELISA. Skin testing supported the results of the ELISAs and demonstrated loss of skin test reactivity to the sodium hypochlorite–treated mold solutions in most of the subjects. Of the 4 individuals who had a positive skin test result to mold
grown on oriented strand board building material, 3 no longer reacted to extracts from bleach-treated boards.
Conclusion: Spray application of sodium hypochlorite–containing disinfectants onto mold-contaminated building material kills A fumigatus, modifies the surface characteristics of A fumigatus conidia, reduces recognition of A fumigatus mold by ELISA, and results in loss of skin test reactivity to the treated mold in individuals allergic to A fumigatus. (J Allergy
Clin Immunol 2005;116:630-5.)