Preparative HPLC puri- fications were performed on a CXTH LC3000 HPLC system (Beijing Chuangxintongheng Co., Beijing, China) equipped with a SIELC Primesep P semipreparative (10 x 250 mm, 5 um) column,eluting with acetonitrile/0.1% aq.formic acid isochratic systems.