Definition
Nephrotic syndrome is characterized by high urine protein excretion (>3.5 g/1.73 m3/24 hr), peripheral edema, and metabolic abnormalities (hypoalbuminemia, hypercholesterolemia). Table 1-358 describes definitions of terms used in idiopathic nephrotic syndrome in adults and children. Fig. 1-651 illustrates the mechanism of nephrotic edema