A kinase annotated as a PKA, PKG, and PKC
(AGC) kinase subfamily member was reported to
localize to the cytoplasm and to the caudal side of
trophozoites by means of heterologous antibodies
against mammalian PKCbetaII (Bazan-Tejeda et al.,
2007). Within minutes after induction of encystation, this protein translocates from the cytoplasm to
the membrane, suggesting it is activated. However,
within 30 min, it localized back in the cytoplasm. The
protein levels were very low in vegetative cells but
increased in encystation (Bazan-Tejeda et al., 2007).