MicroRNAs (miRNAs) are small, single stranded, non coding RNAs which are approximately of 22 nucleotides that form base pairs with target messenger RNAs, leading to negatively regulate translation of targeted protein. (Bartel DP, 2004). MicroRNA regulate fundamental cellular processes including proliferation, development, cellular differentiation, hematopoiesis, immune responses and regulation of gene expression. More than 2,500 human miRNAs have been discovered and is believed to regulate multigenes. (Hayes J et al., 2014).