In 1994, the
organism was classified into group I, carcinogenic to
humans, by the World Health Organization/International
Agency for Research on Cancer (WHO/IARC)
Although triple therapy using two antibiotics (amoxicillin
and clarithromycin) and a proton pump inhibitor is
widely employed in the treatment of H. pylori, antibiotic
resistance to clarithromycin leads to treatment failure,
especially in Asian countries.