FVIII expression in SCID mice
Before Dox administration beginning at 1-week post- transplantation, hFVIII:Ag was undetectable in the plasma of treated mice. hFVIII:Ag was also undetectable in untrans- planted mice, even after Dox administration. At 1-week post-Dox administration (2-weeks post-transplantation), we detected elevated levels of hFVIII:Ag in all three mice.