The identification of a single active chemical entity that is
responsible for the antimicrobial activity of a plant is becoming
more and more improbable. Research should be focussing
on the investigation of a combination of compounds to achieve
a greater efficacy. To ensure future success in natural product
research we must incorporate interactive phytochemical
studies with existing practices in the hope that developments
involving combinations may be used as a foundation
and driving force in the search for novel chemotherapeutic
agents.