results: sixty percent of these patients had depressive symptomatology. The severity of comorbidity (Charlson index) was 4 and the patient perception of quality of life (Short Form-12 scores) were between 79 and 82. The pervalence of no adherence was 70% even with a low MPR of 0.2. Insomnia patients with depressive symptoms were 92% less likely to be adherent to their insomnia medications (p<0.05)After controlling other variable ,we found MPR was a good predictor of total health care costs(10% increases in MPR for every 2% decrease in total health care costs,p<0.001)
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